Current Problems in Surgery
Volume 43, Issue 8 , Pages 566-670 , August 2006

Current Problems in Surgery: Gastric Cancer

  • Clancy J. Clark, MD

      Affiliations

    • Department of General Surgery, Virginia Mason Medical Center, Seattle, Washington
    • ,
  • Richard C. Thirlby, MD

      Affiliations

    • Department of General Surgery, Virginia Mason Medical Center, Seattle, Washington
    • ,
  • Vicent Picozzi Jr., MD

      Affiliations

    • Department of Hematology-Oncology, Virginia Mason Medical Center, Seattle, Washington
    • ,
  • Drew B. Schembre, MD

      Affiliations

    • Department of Gastroenterology, Virginia Mason Medical Center, Seattle, Washington
    • ,
  • Felicia P. Cummings, MD

      Affiliations

    • Department of Radiology, Virginia Mason Medical Center, Seattle, Washington
    • ,
  • Eugene Lin, MD

      Affiliations

    • Department of Radiology, Virginia Mason Medical Center, Seattle, Washington

References 

  1. Ferlay J , Bray F , Pisani P , Parkin DM . GLOBOCAN 2002: Cancer Incidence, Mortality and Prevalence Worldwide . Lyon: IARC Press; 2004;
  2. Parkin DM , Whelan SL , Ferlay J , Storm H . Cancer Incidence in Five Continents, Vol. I to VIII . Lyon: IARC Press; 2005;
  3. Corella D , Guillen M . Dietary habits and epidemiology of gastric carcinoma . Hepatogastroenterology . 2001;48:1537–1543
  4. Ries L, Eisner M, Kosary C, Hankey B, Miller B, Clegg L, et al. SEER Cancer Statistics Review . 1975-2002;
  5. Tsugane S , de Souza JM , Costa ML , Mirra AP , Gotlieb SL , Laurenti R , et al.   Cancer incidence rates among Japanese immigrants in the city of Sao Paulo, Brazil, 1969-78 . Cancer Causes Control . 1990;1:189–193
  6. Stemmermann GN . Gastric cancer in the Hawaii . Japanese Gann . 1977;68:525–535
  7. Coggon D , Barker DJ , Cole RB , Nelson M . Stomach cancer and food storage . J Natl Cancer Inst . 1989;81:1178–1182
  8. Boeing H , Frentzel-Beyme R , Berger M , Berndt V , Gores W , et al.   Case-control study on stomach cancer in Germany . Int J Cancer . 1991;47:858–864
  9. Munoz N , Plummer M , Vivas J , Moreno V , De SS , Lopez G , et al.   A case-control study of gastric cancer in Venezuela . Int J Cancer . 2001;93:417–423
  10. Jedrychowski W , Boeing H , Popiela T , Wahrendorf J , Tobiasz-Adamczyk B , Kulig J . Dietary practices in households as risk factors for stomach cancer: a familial study in Poland . Eur J Cancer Prev . 1992;1:297–304
  11. van den Brandt PA , Botterweck AA , Goldbohm RA . Salt intake, cured meat consumption, refrigerator use and stomach cancer incidence: a prospective cohort study (Netherlands) . Cancer Causes Control . 2003;14:427–438
  12. Devesa SS , Blot WJ , Fraumeni JF . Changing patterns in the incidence of esophageal and gastric carcinoma in the United States . Cancer . 1998;83:2049–2053
  13. Locke GR , Talley NJ , Carpenter HA , Harmsen WS , Zinsmeister AR , Melton LJ . Changes in the site- and histology-specific incidence of gastric cancer during a 50-year period . Gastroenterology . 1995;109:1750–1756
  14. Shang J , Pena AS . Multidisciplinary approach to understand the pathogenesis of gastric cancer . World J Gastroenterol . 2005;11:4131–4139
  15. Kubo A , Corley DA . Marked multi-ethnic variation of esophageal and gastric cardia carcinomas within the United States . Am J Gastroenterol . 2004;99:582–588
  16. Blot WJ , Devesa SS , Kneller RW , Fraumeni JF . Rising incidence of adenocarcinoma of the esophagus and gastric cardia . JAMA . 1991;265:1287–1289
  17. Wang WH , Huang JQ , Zheng GF , Lam SK , Karlberg J , Wong BC . Non-steroidal anti-inflammatory drug use and the risk of gastric cancer: a systematic review and meta-analysis . J Natl Cancer Inst . 2003;95:1784–1791
  18. Correa P , Piazuelo MB , Camargo MC . The future of gastric cancer prevention . Gastric Cancer . 2004;7:9–16
  19. Watson P , Lynch HT . Extracolonic cancer in hereditary nonpolyposis colorectal cancer . Cancer . 1993;71:677–685
  20. Aarnio M , Salovaara R , Aaltonen LA , Mecklin JP , Jarvinen HJ . Features of gastric cancer in hereditary non-polyposis colorectal cancer syndrome . Int J Cancer . 1997;74:551–555
  21. Theuer CP , Campbell BS , Peel DJ , Lin F , Carpenter P , Ziogas A , et al.   Microsatellite instability in Japanese vs European American patients with gastric cancer . Arch Surg . 2002;137:960–965
  22. Caldas C , Carneiro F , Lynch HT , Yokota J , Wiesner GL , Powell SM , et al.   Familial gastric cancer: overview and guidelines for management . J Med Genet . 1999;36:873–880
  23. Guilford P , Hopkins J , Harraway J , McLeod M , McLeod N , Harawira P , et al.   E-cadherin germline mutations in familial gastric cancer . Nature . 1998;392(6674):402–405
  24. Becker KF , Atkinson MJ , Reich U , Becker I , Nekarda H , Siewert JR , et al.   E-cadherin gene mutations provide clues to diffuse type gastric carcinomas . Cancer Res . 1994;54:3845–3852
  25. Tahara E . Mechanisms of carcinogenesis: contributions of molecular epidemiology . In:  Buffler PA editors. Mechanisms of Carcinogenesis: Contributions of Molecular Epidemiology . Lyon: International Agency for Research on Cancer; 2004;p. 327–349
  26. World Health Organization . Diet, Nutrition, and the Prevention of Chronic Diseases: Report of a Joint WHO/FAO Expert Consultation . Geneva: World Health Organization; 2003;
  27. Tsugane S . Salt, salted food intake, and risk of gastric cancer: epidemiologic evidence . Cancer Sci . 2005;96:1–6
  28. Sugimura T , Fujimura S . Tumour production in glandular stomach of rat by N-methyl-N′-nitro-N-nitrosoguanidine . Nature . 1967;216(118):943–944
  29. Yamaguchi N , Kakizoe T . Synergistic interaction between Helicobacter pylori gastritis and diet in gastric cancer . Lancet Oncol . 2001;2:88–94
  30. Blot WJ , Li JY , Taylor PR , Guo W , Dawsey S , Wang GQ , et al.   Nutrition intervention trials in Linxian, China: supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population . J Natl Cancer Inst . 1993;85:1483–1492
  31. Albanes D , Heinonen OP , Taylor PR , Virtamo J , Edwards BK , Rautalahti M , et al.   Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance . J Natl Cancer Inst . 1996;88:1560–1570
  32. Virtamo J , Pietinen P , Huttunen JK , Korhonen P , Malila N , Virtanen MJ , et al.   Incidence of cancer and mortality following alpha-tocopherol and beta-carotene supplementation: a postintervention follow-up . JAMA . 2003;290:476–485
  33. Tredaniel J , Boffetta P , Buiatti E , Saracci R , Hirsch A . Tobacco smoking and gastric cancer: review and meta-analysis . Int J Cancer . 1997;72:565–573
  34. Gammon MD , Schoenberg JB , Ahsan H , Risch HA , Vaughan TL , Chow WH , et al.   Tobacco, alcohol, and socioeconomic status and adenocarcinomas of the esophagus and gastric cardia . J Natl Cancer Inst . 1997;89:1277–1284
  35. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans International Agency for Research on Cancer National Cancer Institute (U.S.) . Alcohol Drinking . Lyon, France: World Health Organization, International Agency for Research on Cancer; 1988;
  36. World Cancer RF American Institute for Cancer Research . Food, Nutrition, and the Prevention of Cancer: A Global Perspective . Washington, DC: The Institute; 1997;
  37. Warren J . Unidentified curved bacilli on gastric epithelium in active chronic gastritis . Lancet . 1983;1:1273–1275
  38. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans . Schistosomes, liver flukes and Helicobacter pylori (Lyon, 7-14 June 1994) . IARC Monogr Eval Carcinog Risks Hum . 1994;61:1–241
  39. Huang JQ , Sridhar S , Chen Y , Hunt RH . Meta-analysis of the relationship between Helicobacter pylori seropositivity and gastric cancer . Gastroenterology . 1998;114:1169–1179
  40. Holcombe C . Helicobacter pylori: the African enigma . Gut . 1992;33:429–431
  41. Marshall BJ , Windsor HM . The relation of Helicobacter pylori to gastric adenocarcinoma and lymphoma: pathophysiology, epidemiology, screening, clinical presentation, treatment, and prevention . Med Clin North Am . 2005;89:313–344 viii
  42. Malaty HM , Graham DY . Importance of childhood socioeconomic status on the current prevalence of Helicobacter pylori infection . Gut . 1994;35:742–745
  43. Staat MA , Kruszon-Moran D , McQuillan GM , Kaslow RA . A population-based serologic survey of Helicobacter pylori infection in children and adolescents in the United States . J Infect Dis . 1996;174:1120–1123
  44. El-Omar EM , Carrington M , Chow WH , McColl KE , Bream JH , Young HA , et al.   Interleukin-1 polymorphisms associated with increased risk of gastric cancer . Nature . 2000;404(6776):398–402
  45. Zagari RM , Bazzoli F . Gastric cancer: who is at risk? . Dig Dis . 2004;22:302–305
  46. Sugiyama A , Maruta F , Ikeno T , Ishida K , Kawasaki S , Katsuyama T , et al.   Helicobacter pylori infection enhances N-methyl-N-nitrosourea-induced stomach carcinogenesis in the Mongolian gerbil . Cancer Res . 1998;58:2067–2069
  47. Nomura A , Stemmermann GN , Chyou PH , Kato I , Perez-Perez GI , Blaser MJ . Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii . N Engl J Med . 1991;325:1132–1136
  48. Parsonnet J , Friedman GD , Vandersteen DP , Chang Y , Vogelman JH , Orentreich N , et al.   Helicobacter pylori infection and the risk of gastric carcinoma . N Engl J Med . 1991;325:1127–1131
  49. The EUROGAST Study Group . An international association between Helicobacter pylori infection and gastric cancer . Lancet . 1993;341:1359–1362
  50. Uemura N , Mukai T , Okamoto S , Yamaguchi S , Mashiba H , Taniyama K , et al.   Effect of Helicobacter pylori eradication on subsequent development of cancer after endoscopic resection of early gastric cancer . Cancer Epidemiol Biomarkers Prev . 1997;6:639–642
  51. Uemura N , Okamoto S , Yamamoto S , Matsumura N , Yamaguchi S , Yamakido M , et al.   Helicobacter pylori infection and the development of gastric cancer . N Engl J Med . 2001;345:784–789
  52. Ebert MP , Leodolter A , Malfertheiner P . Novel strategies in the prevention of gastric cancer . Hepatogastroenterology . 2001;48(42):1569–1571
  53. Wong BC , Lam SK , Wong WM , Chen JS , Zheng TT , Feng RE , et al.   Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial . JAMA . 2004;291:187–194
  54. Malfertheiner P , Sipponen P , Naumann M , Moayyedi P , Megraud F , Xiao SD , et al.   Helicobacter pylori eradication has the potential to prevent gastric cancer: a state-of-the-art critique . Am J Gastroenterol . 2005;100:2100–2115
  55. Aranha GV , Georgen R . Gastric linitis plastica is not a surgical disease . Surgery . 1989;106:758–762
  56. Gertsch P , Yip SK , Chow LW , Lauder IJ . Free perforation of gastric carcinoma (Results of surgical treatment) . Arch Surg . 1995;130:177–181
  57. Allum WH , Brearley S , Wheatley KE , Dykes PW , Keighley MR . Acute haemorrhage from gastric malignancy . Br J Surg . 1990;77:19–20
  58. Inoue M , Tsugane S . Epidemiology of gastric cancer in Japan . Postgrad Med J . 2005;81(957):419–424
  59. Maruyama M , Barreto-Zuniga R , Kimura K . Misconceptions on early gastric cancer in Japan . Hepatogastroenterology . 2001;48(42):1560–1564
  60. Stael von HC , Eriksson S , Huldt B , Hammar E . Endoscopic screening during 17 years for gastric stump carcinoma (A prospective clinical trial) . Scand J Gastroenterol . 1991;26:1020–1026
  61. Everett SM , Axon AT . Early gastric cancer: disease or pseudo-disease? . Lancet . 1998;351:1350–1352
  62. Wobbes T , Thomas CM , Segers MF , Nagengast FM . Evaluation of seven tumor markers (CA 50, CA 19-9, CA 19-9 TruQuant, CA 72-4, CA 195, carcinoembryonic antigen, and tissue polypeptide antigen) in the pretreatment sera of patients with gastric carcinoma . Cancer . 1992;69:2036–2041
  63. Chan AO , Chu KM , Lam SK , Cheung KL , Law S , Kwok KF , et al.   Early prediction of tumor recurrence after curative resection of gastric carcinoma by measuring soluble E-cadherin . Cancer . 2005;104:740–746
  64. Karayiannakis AJ , Syrigos KN , Polychronidis A , Zbar A , Kouraklis G , Simopoulos C , et al.   Circulating VEGF levels in the serum of gastric cancer patients: correlation with pathological variables, patient survival, and tumor surgery . Ann Surg . 2002;236:37–42
  65. Chen J , Rocken C , Malfertheiner P , Ebert MP . Recent advances in molecular diagnosis and therapy of gastric cancer . Dig Dis . 2004;22:380–385
  66. Tay ST , Leong SH , Yu K , Aggarwal A , Tan SY , Lee CH , et al.   A combined comparative genomic hybridization and expression microarray analysis of gastric cancer reveals novel molecular subtypes . Cancer Res . 2003;63:3309–3316
  67. Yasui W , Oue N , Ito R , Kuraoka K , Nakayama H . Search for new biomarkers of gastric cancer through serial analysis of gene expression and its clinical implications . Cancer Sci . 2004;95:385–392
  68. Tomlinson AJ , Hincapie M , Morris GE , Chicz RM . Global proteome analysis of a human gastric carcinoma . Electrophoresis . 2002;23:3233–3240
  69. Halvorsen RA , Yee J , McCormick VD . Diagnosis and staging of gastric cancer . Semin Oncol . 1996;23:325–335
  70. Low VH , Levine MS , Rubesin SE , Laufer I , Herlinger H . Diagnosis of gastric carcinoma: sensitivity of double-contrast barium studies . AJR Am J Roentgenol . 1994;162:329–334
  71. Japanese Research Society for Gastric Cancer . The general rules for the gastric cancer study in surgery . Jpn J Surg . 1973;3:61–71
  72. Fuchs CS , Mayer RJ . Gastric carcinoma . N Engl J Med . 1995;333:32–41
  73. Gore RM , Levine MS . Textbook of gastrointestinal surgery . 2nd ed.. Philadelphia: WB Saunders; 2000;
  74. Levine MS , Creteur V , Kressel HY , Laufer I , Herlinger H . Benign gastric ulcers: diagnosis and follow-up with double-contrast radiography . Radiology . 1987;164:9–13
  75. Thompson G , Somers S , Stevenson GW . Benign gastric ulcer: a reliable radiologic diagnosis? . AJR Am J Roentgenol . 1983;141:331–333
  76. Shindoh N , Nakagawa T , Ozaki Y , Kyogoku S , Sumi Y , Katayama H . Overlooked gastric carcinoma: pitfalls in upper gastrointestinal radiology . Radiology . 2000;217:409–414
  77. Japanese classification of gastric carcinoma. 2nd English edition. Response assessment of chemotherapy and radiotherapy for gastric carcinoma: clinical criteria . Gastric Cancer . 2001;4:1–8
  78. Ming SC . Gastric carcinoma (A pathobiological classification) . Cancer . 1977;39:2475–2485
  79. Lauren P . The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma (an attempt at a histo-clinical classification) . Acta Pathol Microbiol Scand . 1965;64:31–49
  80. Cunningham SC , Kamangar F , Kim MP , Hammoud S , Haque R , Maitra A , et al.   Survival after gastric adenocarcinoma resection: eighteen-year experience at a single institution . J Gastrointest Surg . 2005;9:718–725
  81. Wu MS , Shun CT , Wang HP , Sheu JC , Lee WJ , Wang TH , et al.   Genetic alterations in gastric cancer: relation to histological subtypes, tumor stage, and Helicobacter pylori infection . Gastroenterology . 1997;112:1457–1465
  82. Kokkola A , Sipponen P . Gastric carcinoma in young adults . Hepatogastroenterology . 2001;48:1552–1555
  83. Hansson LE , Sparen P , Nyren O . Survival in stomach cancer is improving: results of a nationwide population-based Swedish study . Ann Surg . 1999;230:162–169
  84. Buzzoni R , Bajetta E , Di BM , Miceli R , Beretta E , Ferrario E , et al.   Pathological features as predictors of recurrence after radical resection of gastric cancer . Br J Surg . 2005;93:205–209
  85. Roder JD , Bottcher K , Busch R , Wittekind C , Hermanek P , Siewert JR  German Gastric Cancer Study Group . Classification of regional lymph node metastasis from gastric carcinoma . Cancer . 1998;82:621–631
  86. Siewert JR , Bottcher K , Stein HJ , Roder JD . Relevant prognostic factors in gastric cancer: ten-year results of the German Gastric Cancer Study . Ann Surg . 1998;228:449–461
  87. Schott A , Vogel I , Krueger U , Kalthoff H , Schreiber HW , Schmiegel W , et al.   Isolated tumor cells are frequently detectable in the peritoneal cavity of gastric and colorectal cancer patients and serve as a new prognostic marker . Ann Surg . 1998;227:372–379
  88. Kodera Y , Nakanishi H , Ito S , Mochizuki Y , Ohashi N , Yamamura Y , et al.   Prognostic significance of intraperitoneal cancer cells in gastric carcinoma: analysis of real time reverse transcriptase-polymerase chain reaction after 5 years of followup . J Am Coll Surg . 2006;202:231–236
  89. Jonas S , Weinrich M , Tullius SG , Al-Abadi H , Steinbrich R , Radke C , et al.   Microscopic tumor cell dissemination in gastric cancer . Surg Today . 2004;34:101–106
  90. Yasuda K , Adachi Y , Shiraishi N , Inomata M , Takeuchi H , Kitano S . Prognostic effect of lymph node micrometastasis in patients with histologically node-negative gastric cancer . Ann Surg Oncol . 2002;9:771–774
  91. Siewert JR , Feith M , Werner M , Stein HJ . Adenocarcinoma of the esophagogastric junction: results of surgical therapy based on anatomical/topographic classification in 1,002 consecutive patients . Ann Surg . 2000;232:353–361
  92. Hundahl SA , Macdonald JS , Benedetti J , Fitzsimmons T . Surgical treatment variation in a prospective, randomized trial of chemoradiotherapy in gastric cancer: the effect of undertreatment . Ann Surg Oncol . 2002;9:278–286
  93. Marrelli D, Roviello F, De SA, Fotia G, Giliberto C, Garosi L, et al. Risk factors for liver metastases after curative surgical procedures for gastric cancer: a prospective study of 208 patients treated with surgical resection . J Am Coll Surg . 2004;198:51–58
  94. Kim SH , Karpeh MS , Klimstra DS , Leung D , Brennan MF . Effect of microscopic resection line disease on gastric cancer survival . J Gastrointest Surg . 1999;3:24–33
  95. Novotny AR , Schuhmacher C , Busch R , Kattan MW , Brennan MF , Siewert JR . Predicting individual survival after gastric cancer resection: validation of a U.S.-derived nomogram at a single high-volume center in Europe . Ann Surg . 2006;243:74–81
  96. Dicken BJ , Graham K , Hamilton SM , Andrews S , Lai R , Listgarten J , et al.   Lymphovascular invasion is associated with poor survival in gastric cancer: an application of gene-expression and tissue array techniques . Ann Surg . 2006;243:64–73
  97. Marrelli D , DeStefano A , deManzoni G , Morgagni P , DiLeo A , Roviello F . Prediction of recurrence after radical surgery for gastric cancer: a scoring system obtained from a prospective multicenter study . Ann Surg . 2005;241:247–255
  98. Roesch T . Endoscopic ultrasonography: equipment and technique . Gastrointest Endosc Clin N Am . 2005;15:13–31 vii
  99. Paramo JC , Gomez G . Dynamic CT in the preoperative evaluation of patients with gastric cancer: correlation with surgical findings and pathology . Ann Surg Oncol . 1999;6:379–384
  100. Davies J , Chalmers AG , Sue-Ling HM , May J , Miller GV , Martin IG , et al.   Spiral computed tomography and operative staging of gastric carcinoma: a comparison with histopathological staging . Gut . 1997;41:314–319
  101. Willis S , Truong S , Gribnitz S , Fass J , Schumpelick V . Endoscopic ultrasonography in the preoperative staging of gastric cancer: accuracy and impact on surgical therapy . Surg Endosc . 2000;14:951–954
  102. Kelly S , Harris KM , Berry E , Hutton J , Roderick P , Cullingworth J , et al.   A systematic review of the staging performance of endoscopic ultrasound in gastro-oesophageal carcinoma . Gut . 2001;49:534–539
  103. Bhandari S , Shim CS , Kim JH , Jung IS , Cho JY , Lee JS , et al.   Usefulness of three-dimensional, multidetector row CT (virtual gastroscopy and multiplanar reconstruction) in the evaluation of gastric cancer: a comparison with conventional endoscopy, EUS, and histopathology . Gastrointest Endosc . 2004;59:619–626
  104. Aithal GP , Anagnostopoulos GK , Kaye P . EUS-guided Trucut mural biopsies in the investigation of unexplained thickening of the esophagogastric wall . Gastrointest Endosc . 2005;62:624–629
  105. Nguyen PT , Chang KJ . EUS in the detection of ascites and EUS-guided paracentesis . Gastrointest Endosc . 2001;54:336–339
  106. Prasad P , Schmulewitz N , Patel A , Varadarajulu S , Wildi SM , Roberts S , et al.   Detection of occult liver metastases during EUS for staging of malignancies . Gastrointest Endosc . 2004;59:49–53
  107. Raju GS , Waxman I . High-frequency US probe sonography-assisted endoscopic mucosal resection . Gastrointest Endosc . 2000;52(6 Suppl):S39–S49
  108. Buskens CJ , Westerterp M , Lagarde SM , Bergman JJ , ten Kate FJ , van Lanschot JJ . Prediction of appropriateness of local endoscopic treatment for high-grade dysplasia and early adenocarcinoma by EUS and histopathologic features . Gastrointest Endosc . 2004;60:703–710
  109. Marks WM , Callen PW , Moss AA . Gastroesophageal region: source of confusion on CT . AJR Am J Roentgenol . 1981;136:359–362
  110. Botet JF , Lightdale CJ , Zauber AG , Gerdes H , Winawer SJ , Urmacher C , et al.   Preoperative staging of gastric cancer: comparison of endoscopic US and dynamic CT . Radiology . 1991;181:426–432
  111. Habermann CR , Weiss F , Riecken R , Honarpisheh H , Bohnacker S , Staedtler C , et al.   Preoperative staging of gastric adenocarcinoma: comparison of helical CT and endoscopic US . Radiology . 2004;230:465–471
  112. Dux M , Richter GM , Hansmann J , Kuntz C , Kauffmann GW . Helical hydro-CT for diagnosis and staging of gastric carcinoma . J Comput Assist Tomogr . 1999;23:913–922
  113. Fukuya T , Honda H , Kaneko K , Kuroiwa T , Yoshimitsu K , Irie H , et al.   Efficacy of helical CT in T-staging of gastric cancer . J Comput Assist Tomogr . 1997;21:73–81
  114. Kumano S , Murakami T , Kim T , Hori M , Iannaccone R , Nakata S , et al.   T staging of gastric cancer: role of multi-detector row CT . Radiology . 2005;237:961–966
  115. Lee JH, Jeong YK, Kim DH, Go BK, Woo YJ, Ham SY, et al. Two-phase helical CT for detection of early gastric carcinoma: importance of the mucosal phase for analysis of the abnormal mucosal layer . J Comput Assist Tomogr . 2000;24:777–782
  116. Shimizu K , Ito K , Matsunaga N , Shimizu A , Kawakami Y . Diagnosis of gastric cancer with mdct using the water-filling method and multiplanar reconstruction: CT-histologic correlation . AJR Am J Roentgenol . 2005;185:1152–1158
  117. Takao M , Fukuda T , Iwanaga S , Hayashi K , Kusano H , Okudaira S . Gastric cancer: evaluation of triphasic spiral CT and radiologic-pathologic correlation . J Comput Assist Tomogr . 1998;22:288–294
  118. Minami M , Kawauchi N , Itai Y , Niki T , Sasaki Y . Gastric tumors: radiologic-pathologic correlation and accuracy of T staging with dynamic CT . Radiology . 1992;185:173–178
  119. Tsuda K , Hori S , Murakami T , Nakamura H , Tomoda K , Nakanishi K , et al.   Intramural invasion of gastric cancer: evaluation by CT with water-filling method . J Comput Assist Tomogr . 1995;19:941–947
  120. Fukuya T , Honda H , Hayashi T , Kaneko K , Tateshi Y , Ro T , et al.   Lymph-node metastases: efficacy for detection with helical CT in patients with gastric cancer . Radiology . 1995;197:705–711
  121. Kim AY , Han JK , Seong CK , Kim TK , Choi BI . MRI in staging advanced gastric cancer: is it useful compared with spiral CT? . J Comput Assist Tomogr . 2000;24:389–394
  122. Sohn KM , Lee JM , Lee SY , Ahn BY , Park SM , Kim KM . Comparing MR imaging and CT in the staging of gastric carcinoma . AJR Am J Roentgenol . 2000;174:1551–1557
  123. Antoch G , Saoudi N , Kuehl H , Dahmen G , Mueller SP , Beyer T , et al.   Accuracy of whole-body dual-modality fluorine-18-2-fluoro-2-deoxy-d-glucose positron emission tomography and computed tomography (FDG-PET/CT) for tumor staging in solid tumors: comparison with CT and PET . J Clin Oncol . 2004;22(1):4357–4368
  124. Chen J , Cheong JH , Yun MJ , Kim J , Lim JS , Hyung WJ , et al.   Improvement in preoperative staging of gastric adenocarcinoma with positron emission tomography . Cancer . 2005;103:2383–2390
  125. Kim SK , Kang KW , Lee JS , Kim HK , Chang HJ , Choi JY , et al.   Assessment of lymph node metastases using (18)F-FDG PET in patients with advanced gastric cancer . Eur J Nucl Med Mol Imaging . 2005;33:148–155
  126. Stahl A , Ott K , Weber WA , Becker K , Link T , Siewert JR , et al.   FDG PET imaging of locally advanced gastric carcinomas: correlation with endoscopic and histopathological findings . Eur J Nucl Med Mol Imaging . 2003;30:288–295
  127. Mochiki E , Kuwano H , Katoh H , Asao T , Oriuchi N , Endo K . Evaluation of 18F-2-deoxy-2-fluoro-D-glucose positron emission tomography for gastric cancer . World J Surg . 2004;28:247–253
  128. Yoshioka T , Yamaguchi K , Kubota K , Saginoya T , Yamazaki T , Ido T , et al.   Evaluation of 18F-FDG PET in patients with a metastatic, or recurrent, gastric cancer . J Nucl Med . 2003;44:690–699
  129. Yun M , Lim JS , Noh SH , Hyung WJ , Cheong JH , Bong JK , et al.   Lymph node staging of gastric cancer using (18)F-FDG PET: a comparison study with CT . J Nucl Med . 2005;46:1582–1588
  130. De Potter T , Flamen P , Van CE , Penninckx F , Filez L , Bormans G , et al.   Whole-body PET with FDG for the diagnosis of recurrent gastric cancer . Eur J Nucl Med Mol Imaging . 2002;29:525–529
  131. Ott K , Fink U , Becker K , Stahl A , Dittler HJ , Busch R , et al.   Prediction of response to preoperative chemotherapy in gastric carcinoma by metabolic imaging: results of a prospective trial . J Clin Oncol . 2003;21:4604–4610
  132. Shandall A , Johnson C . Laparoscopy or scanning in oesophageal and gastric carcinoma? . Br J Surg . 1985;72:449–451
  133. Gross E , Bancewicz J , Ingram G . Assessment of gastric cancer by laparoscopy . Br Med J (Clin Res Ed) . 1984;288:1577; (letter)
  134. Watt I , Stewart I , Anderson D , Bell G , Anderson JR . Laparoscopy, ultrasound and computed tomography in cancer of the oesophagus and gastric cardia: a prospective comparison for detecting intra-abdominal metastases . Br J Surg . 1989;76:1036–1039
  135. Tschmelitsch J , Weiser MR , Karpeh MS . Modern staging in gastric cancer . Surg Oncol . 2000;9:23–30
  136. Molloy RG , McCourtney JS , Anderson JR . Laparoscopy in the management of patients with cancer of the gastric cardia and oesophagus . Br J Surg . 1995;82:352–354
  137. Kriplani AK , Kapur BM . Laparoscopy for pre-operative staging and assessment of operability in gastric carcinoma . Gastrointest Endosc . 1991;37:441–443
  138. Burke EC , Karpeh MS , Conlon KC , Brennan MF . Laparoscopy in the management of gastric adenocarcinoma . Ann Surg . 1997;225:262–267
  139. Finch MD , John TG , Garden OJ , Allan PL , Paterson-Brown S . Laparoscopic ultrasonography for staging gastroesophageal cancer . Surgery . 1997;121:10–17
  140. Jaffer A, Bekaii-Saab T, Javie M, Minsky B. Gastric Cancer Clinical Practice Guidelines in Oncology. http://www.nccn.org/professionals/physician_gls/PDF/gastric.pdf, 2006, v.1.2006, accessed 8/22/2006
  141. D’Ugo DM , Pende V , Persiani R , Rausei S , Picciocchi A . Laparoscopic staging of gastric cancer: an overview . J Am Coll Surg . 2003;196:965–974
  142. Inada T , Ogata Y , Kubota T , Ishihara M , Tomikawa M , Ando J , et al.   D2-lymphadenectomy improves the survival of patients with peritoneal cytology-positive gastric cancer . Anticancer Res . 2002;22:291–294
  143. Scartozzi M , Galizia E , Graziano F , Catalano V , Berardi R , Baldelli AM , et al.   Over-DI dissection may question the value of radiotherapy as a part of an adjuvant programme in high-risk radically resected gastric cancer patients . Br J Cancer . 2005;92(28):1051–1054
  144. Harrison LE , Karpeh MS , Brennan MF . Extended lymphadenectomy is associated with a survival benefit for node-negative gastric cancer . J Gastrointest Surg . 1998;2:126–131
  145. Cuschieri A , Weeden S , Fielding J , Bancewicz J , Craven J , Joypaul V , et al.  Surgical Co-operative Group   Patient survival after D1 and D2 resections for gastric cancer: long-term results of the MRC randomized surgical trial . Br J Cancer . 1999;79(9-10):1522–1530
  146. Bonenkamp JJ , Hermans J , Sasako M , van de Velde CJ , Welvaart K , Songun I , et al.   Extended lymph-node dissection for gastric cancer . N Engl J Med . 1999;340:908–914
  147. Fatouros M , Roukos DH , Lorenz M , Arampatzis I , Hottentrott C , Encke A , et al.   Impact of spleen preservation in patients with gastric cancer . Anticancer Res . 2005;25:3023–3030
  148. Brady MS , Rogatko A , Dent LL , Shiu MH . Effect of splenectomy on morbidity and survival following curative gastrectomy for carcinoma . Arch Surg . 1991;126:359–364
  149. Griffith JP , Sue-Ling HM , Martin I , Dixon MF , McMahon MJ , Axon AT , et al.   Preservation of the spleen improves survival after radical surgery for gastric cancer . Gut . 1995;36:684–690
  150. Smith JW , Shiu MH , Kelsey L , Brennan MF . Morbidity of radical lymphadenectomy in the curative resection of gastric carcinoma . Arch Surg . 1991;126:1469–1473
  151. Edwards P , Blackshaw GR , Lewis WG , Barry JD , Allison MC , Jones DR . Prospective comparison of D1 vs modified D2 gastrectomy for carcinoma . Br J Cancer . 2004;90:1888–1892
  152. McCulloch P , Nita ME , Kazi H , Gama-Rodrigues J . Extended versus limited lymph nodes dissection technique for adenocarcinoma of the stomach . Cochrane Database Syst Rev . 2004;(4): CD001964
  153. Jansen EP , Boot H , Verheij M , van de Velde CJ . Optimal locoregional treatment in gastric cancer . J Clin Oncol . 2005;23:4509–4517
  154. McCulloch P , Niita ME , Kazi H , Gama-Rodrigues JJ . Gastrectomy with extended lymphadenectomy for primary treatment of gastric cancer . Br J Surg . 2005;92:5–13
  155. Karpeh MS , Leon L , Klimstra D , Brennan MF . Lymph node staging in gastric cancer: is location more important than number? (An analysis of 1,038 patients) . Ann Surg . 2000;232:362–371
  156. Bozzetti F , Bonfanti G , Bufalino R , Menotti V , Persano S , Andreola S , et al.   Adequacy of margins of resection in gastrectomy for cancer . Ann Surg . 1982;196:685–690
  157. Harrison LE , Karpeh MS , Brennan MF . Proximal gastric cancers resected via a transabdominal-only approach (Results and comparisons to distal adenocarcinoma of the stomach) . Ann Surg . 1997;225:678–683
  158. Zinninger MM . Extension of gastric cancer in the intramural lymphatics and its relation to gastrectomy . Am Surg . 1954;20:920–927
  159. Gouzi JL , Huguier M , Fagniez PL , Launois B , Flamant Y , Lacaine F , et al.   Total versus subtotal gastrectomy for adenocarcinoma of the gastric antrum (A French prospective controlled study) . Ann Surg . 1989;209:162–166
  160. Robertson CS , Chung SC , Woods SD , Griffin SM , Raimes SA , Lau JT , et al.   A prospective randomized trial comparing R1 subtotal gastrectomy with R3 total gastrectomy for antral cancer . Ann Surg . 1994;220:176–182
  161. Bozzetti F , Marubini E , Bonfanti G , Miceli R , Piano C , Crose N , et al.  The Italian Gastrointestinal Tumor Study Group   Total versus subtotal gastrectomy: surgical morbidity and mortality rates in a multicenter Italian randomized trial . Ann Surg . 1997;226:613–620
  162. Bozzetti F , Marubini E , Bonfanti G , Miceli R , Piano C , Gennari L  Italian Gastrointestinal Tumor Study Group . Subtotal versus total gastrectomy for gastric cancer: five-year survival rates in a multicenter randomized Italian trial . Ann Surg . 1999;230:170–178
  163. Walther BS , Oscarson JE , Graffner HO , Vallgren S , Evander A . Esophagojejunostomy with the EEA stapler . Surgery . 1986;99:598–603
  164. Wong J , Cheung H , Lui R , Fan YW , Smith A , Siu KF . Esophagogastric anastomosis performed with a stapler: the occurrence of leakage and stricture . Surgery . 1987;101:408–415
  165. Seufert RM , Schmidt-Matthiesen A , Beyer A . Total gastrectomy and oesophagojejunostomy—a prospective randomized trial of hand-sutured versus mechanically stapled anastomoses . Br J Surg . 1990;77:50–52
  166. Walther B , Lowenhielm P , Strand SE , Stahlberg F , Uvelius B , Oscarson J , et al.   Healing of esophagojejunal anastomoses after experimental total gastrectomy (A comparative study using manually sutured or stapled anastomoses) . Ann Surg . 1986;203:439–446
  167. Herfarth C , Schlag P , Buhl K . Surgical procedures for gastric substitution . World J Surg . 1987;11:689–698
  168. Nakane Y , Okumura S , Akehira K , Okamura S , Boku T , Okusa T , et al.   Jejunal pouch reconstruction after total gastrectomy for cancer (A randomized controlled trial) . Ann Surg . 1995;222:27–35
  169. Nozoe T , Anai H , Sugimachi K . Usefulness of reconstruction with jejunal pouch in total gastrectomy for gastric cancer in early improvement of nutritional condition . Am J Surg . 2001;181:274–278
  170. Thiede A , Fuchs KH , Hamelman H . Pouch and Roux-en-Y reconstruction after gastrectomy . Arch Surg . 1987;122:837–842
  171. Legaspi A , Irani H . Stapled transabdominal lower esophageal anastomosis without purse-string suture . Surg Gynecol Obstet . 1990;170:156–158
  172. Tejero CE , Ratia GT , Fernandez FL , Tieso HA , Jorge SE . Double-stapling technique for mechanical circular oesophagojejunal anastomosis after total gastrectomy . Br J Surg . 1994;81:408–409
  173. Rohde H , Gebbensleben B , Bauer P , Stutzer H , Zieschang J . Has there been any improvement in the staging of gastric cancer? (Findings from the German Gastric Cancer TNM Study Group) . Cancer . 1989;64:2465–2481
  174. Kobayashi A , Nakagohri T , Konishi M , Inoue K , Takahashi S , Itou M , et al.   Aggressive surgical treatment for T4 gastric cancer . J Gastrointest Surg . 2004;8:464–470
  175. Martin RC , Jaques DP , Brennan MF , Karpeh M . Extended local resection for advanced gastric cancer: increased survival versus increased morbidity . Ann Surg . 2002;236:159–165
  176. Shchepotin IB , Chorny VA , Nauta RJ , Shabahang M , Buras RR , Evans SR . Extended surgical resection in T4 gastric cancer . Am J Surg . 1998;175:123–126
  177. Kunisaki C , Akiyama H , Nomura M , Matsuda G , Otsuka Y , Ono HA , et al.   Surgical outcomes in patients with t4 gastric carcinoma . J Am Coll Surg . 2006;202:223–230
  178. Sandler RS , Johnson MD , Holland KL . Risk of stomach cancer after gastric surgery for benign conditions (A case-control study) . Dig Dis Sci . 1984;29:703–708
  179. Nelson R , Edwards S , Tse B . Prophylactic nasogastric decompression after abdominal surgery . Cochrane Database Syst Rev . 2005;(1): CD004929
  180. Doglietto GB , Papa V , Tortorelli AP , Bossola M , Covino M , Pacelli F . Nasojejunal tube placement after total gastrectomy: a multicenter prospective randomized trial . Arch Surg . 2004;139:1309–1313
  181. Watters JM , Kirkpatrick SM , Norris SB , Shamji FM , Wells GA . Immediate postoperative enteral feeding results in impaired respiratory mechanics and decreased mobility . Ann Surg . 1997;226:369–377
  182. McCarter MD , Gomez ME , Daly JM . Early postoperative enteral feeding following major upper gastrointestinal surgery . J Gastrointest Surg . 1997;1:278–285
  183. Gianotti L , Braga M , Vignali A , Balzano G , Zerbi A , Bisagni P , et al.   Effect of route of delivery and formulation of postoperative nutritional support in patients undergoing major operations for malignant neoplasms . Arch Surg . 1997;132:1222–1229
  184. Senkal M , Zumtobel V , Bauer KH , Marpe B , Wolfram G , Frei A , et al.   Outcome and cost-effectiveness of perioperative enteral immunonutrition in patients undergoing elective upper gastrointestinal tract surgery: a prospective randomized study . Arch Surg . 1999;134:1309–1316
  185. Heys SD , Walker LG , Smith I , Eremin O . Enteral nutritional supplementation with key nutrients in patients with critical illness and cancer: a meta-analysis of randomized controlled clinical trials . Ann Surg . 1999;229:467–477
  186. Kobayashi T , Hisanaga M , Kanehiro H , Yamada Y , Ko S , Nakajima Y . Analysis of risk factors for the development of gallstones after gastrectomy . Br J Surg . 2005;92:1399–1403
  187. Kim J , Lee J , Hyung WJ , Cheong JH , Chen J , Choi SH , et al.   Gastric cancer surgery without drains: a prospective randomized trial . J Gastrointest Surg . 2004;8:727–732
  188. Allum WH , Powell DJ , McConkey CC , Fielding JW . Gastric cancer: a 25-year review . Br J Surg . 1989;76:535–540
  189. McCulloch P , Ward J , Tekkis PP . Mortality and morbidity in gastro-oesophageal cancer surgery: initial results of ASCOT multicentre prospective cohort study . BMJ . 2003;327(22):1192–1197
  190. Park DJ , Lee HJ , Kim HH , Yang HK , Lee KU , Choe KJ . Predictors of operative morbidity and mortality in gastric cancer surgery . Br J Surg . 2005;92:1099–1102
  191. Shchepotin IB , Evans SR , Chorny VA , Shabahang M , Buras RR , Nauta RJ . Postoperative complications requiring relaparotomies after 700 gastrectomies performed for gastric cancer . Am J Surg . 1996;171:270–273
  192. Sasako M , Katai H , Sano T , Maruyama K . Management of complications after gastrectomy with extended lymphadenectomy . Surg Oncol . 2000;9:31–34
  193. Lang H , Piso P , Stukenborg C , Raab R , Jahne J . Management and results of proximal anastomotic leaks in a series of 1114 total gastrectomies for gastric carcinoma . Eur J Surg Oncol . 2000;26:168–171
  194. Langer FB , Wenzl E , Prager G , Salat A , Miholic J , Mang T , et al.   Management of postoperative esophageal leaks with the Polyflex self-expanding covered plastic stent . Ann Thorac Surg . 2005;79:398–403
  195. Kwak HS , Lee JM , Jin GY , Han YM , Yang DH . Treatment of gastrojejunal anastomotic leak with a covered metallic stent . Hepatogastroenterology . 2003;50:62–64
  196. Woods SC , Seeley RJ . Understanding the physiology of obesity: review of recent developments in obesity research . Int J Obes Relat Metab Disord . 2002;26(Suppl 4):S8–S10
  197. Chagnon YC , Perusse L , Weisnagel SJ , Rankinen T , Bouchard C . The human obesity gene map: the 1999 update . Obes Res . 2000;8:89–117
  198. Cummings DE , Weigle DS , Frayo RS , Breen PA , Ma MK , Dellinger EP , et al.   Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery . N Engl J Med . 2002;346:1623–1630
  199. Miholic J , Meyer HJ , Kotzerke J , Balks J , Aebert H , Jahne J , et al.   Emptying of the gastric substitute after total gastrectomy (Jejunal interposition versus Roux-y esophagojejunostomy) . Ann Surg . 1989;210:165–172
  200. Kiyama T , Mizutani T , Okuda T , Fujita I , Tokunaga A , Tajiri T , et al.   Postoperative changes in body composition after gastrectomy . J Gastrointest Surg . 2005;9:313–319
  201. Friess H , Bohm J , Muller MW , Glasbrenner B , Riepl RL , Malfertheiner P , et al.   Maldigestion after total gastrectomy is associated with pancreatic insufficiency . Am J Gastroenterol . 1996;91:341–347
  202. Meyer JH . Nutritional outcomes of gastric operations . In:  Thirlby RC editors. Gastroenterology Clinics of North America . Philadelphia: WB Saunders; 1994;p. 227–260
  203. Stael von Holstein C , Walther B , Ibrahimbegovic E , Akesson B . Nutritional status after total and partial gastrectomy with Roux-en-Y reconstruction . Br J Surg . 1991;78:1084–1087
  204. Bisballe S , Eriksen EF , Melsen F , Mosekilde L , Sorensen OH , Hessov I . Osteopenia and osteomalacia after gastrectomy: interrelations between biochemical markers of bone remodelling, vitamin D metabolites, and bone histomorphometry . Gut . 1991;32:1303–1307
  205. Inoue K , Shiomi K , Higashide S , Kan N , Nio Y , Tobe T , et al.   Metabolic bone disease following gastrectomy: assessment by dual energy X-ray absorptiometry . Br J Surg . 1992;79:321–324
  206. Tovey FI , Hall ML , Ell PJ , Hobsley M . Postgastrectomy osteoporosis . Br J Surg . 1991;78:1335–1337
  207. Wetscher G , Redmond E , Watfah C , Perdikis G , Gadenstatter M , Pointner R . Bone disorders following total gastrectomy . Dig Dis Sci . 1994;39:2511–2515
  208. Kozawa K , Imawari M , Shimazu H , Kobori O , Osuga T , Morioka Y . Vitamin D status after total gastrectomy . Dig Dis Sci . 1984;29:411–416
  209. Suzuki Y , Ishibashi Y , Omura N , Kawasaki N , Kashiwagi H , Yanaga K , et al.   Alendronate improves vitamin D-resistant osteopenia triggered by gastrectomy in patients with gastric cancer followed long term . J Gastrointest Surg . 2005;9:955–960
  210. Northfield TC , Hall CN . Carcinoma of the gastric stump: risks and pathogenesis . Gut . 1990;31:1217–1219
  211. Lundegardh G , Adami HO , Helmick C , Zack M . Risk of cancer following partial gastrectomy for benign ulcer disease . Br J Surg . 1994;81:1164–1167
  212. Mason GR . Perspectives a century later on the “Ansa en Y” of Cesar Roux . Am J Surg . 1991;161:262–265
  213. Toftgaard C . Gastric cancer after peptic ulcer surgery (A historic prospective cohort investigation) . Ann Surg . 1989;210:159–164
  214. Offerhaus GJ , Tersmette AC , Huibregtse K , van de Stadt J , Tersmette KW , Stijnen T , et al.   Mortality caused by stomach cancer after remote partial gastrectomy for benign conditions: 40 years of follow up of an Amsterdam cohort of 2633 postgastrectomy patients . Gut . 1988;29:1588–1590
  215. Stael von Holstein CC , Anderson H , Eriksson SB , Huldt B . Mortality after remote surgery for benign gastroduodenal disease . Gut . 1995;37:617–622
  216. Lundegardh G , Ekbom A , McLaughlin JK , Nyren O . Gastric cancer risk after vagotomy . Gut . 1994;35:946–949
  217. Schafer LW , Larson DE , Melton LJ , Higgins JA , Ilstrup DM . The risk of gastric carcinoma after surgical treatment for benign ulcer disease (A population-based study in Olmsted County, Minnesota) . N Engl J Med . 1983;309:1210–1213
  218. Schnapka G , Hofstaedter F , Schwamberger K , Reissigl H . Gastric stump carcinoma following Billroth II resection for peptic ulcer disease (Comparison with cancer in non-operated stomach) . Endoscopy . 1984;16:171–174
  219. Hansson LE , Nyren O , Hsing AW , Bergstrom R , Josefsson S , Chow WH , et al.   The risk of stomach cancer in patients with gastric or duodenal ulcer disease . N Engl J Med . 1996;335:242–249
  220. Pointner R , Schwab G , Konigsrainer A , Bodner E , Schmid KW . Early cancer of the gastric remnant . Gut . 1988;29:298–301
  221. Greene FL . Early detection of gastric remnant carcinoma (The role of gastroscopic screening) . Arch Surg . 1987;122:300–303
  222. Geboes K , Rutgeerts P , Broeckaert L , Vantrappen G , Desmet V . Histologic appearances of endoscopic gastric mucosal biopsies 10-20 years after partial gastrectomy . Ann Surg . 1980;192:179–182
  223. Marrero JM , de Caestecker JS , Corbishley CM , McCormick C , Northfield TC . Gastric DNA content in postgastrectomy patients (Relationship to mucosal dysplasia) . Cancer . 1996;77:19–24
  224. Offerhaus GJ , van de Stadt J , Huibregtse K , Tersmette AC , Tytgat GN . The mucosa of the gastric remnant harboring malignancy (Histologic findings in the biopsy specimens of 504 asymptomatic patients 15 to 46 years after partial gastrectomy with emphasis on nonmalignant lesions) . Cancer . 1989;64:698–703
  225. Stael von Holstein C , Hammar E , Eriksson S , Huldt B . Clinical significance of dysplasia in gastric remnant biopsy specimens . Cancer . 1993;72:1532–1535
  226. Greene FL . Management of gastric remnant carcinoma based on the results of a 15-year endoscopic screening program . Ann Surg . 1996;223:701–706
  227. Sonnenberg A . Endoscopic screening for gastric stump cancer—would it be beneficial? (A hypothetical cohort study) . Gastroenterology . 1984;87:489–495
  228. Sasako M , Maruyama K , Kinoshita T , Okabayashi K . Surgical treatment of carcinoma of the gastric stump . Br J Surg . 1991;78:822–824
  229. Kodera Y , Yamamura Y , Torii A , Uesaka K , Hirai T , Yasui K , et al.   Gastric remnant carcinoma after partial gastrectomy for benign and malignant gastric lesions . J Am Coll Surg . 1996;182:1–6
  230. Furukawa H , Iwanaga T , Hiratsuka M , Imaoka S , Ishikawa O , Kabuto T , et al.   Gastric remnant cancer as a metachronous multiple lesion . Br J Surg . 1993;80:54–56
  231. Viste A , Eide GE , Glattre E , Soreide O . Cancer of the gastric stump: analyses of 819 patients and comparison with other stomach cancer patients . World J Surg . 1986;10:454–461
  232. Ikeguchi M , Kondou A , Shibata S , Yamashiro H , Tsujitani S , Maeta M , et al.   Clinicopathologic differences between carcinoma in the gastric remnant stump after distal partial gastrectomy for benign gastroduodenal lesions and primary carcinoma in the upper third of the stomach . Cancer . 1994;73:15–21
  233. Eckardt VF , Giessler W , Kanzler G , Remmele W , Bernhard G . Clinical and morphological characteristics of early gastric cancer (A case-control study) . Gastroenterology . 1990;98:708–714
  234. Green PH , O’Toole KM , Weinberg LM , Goldfarb JP . Early gastric cancer . Gastroenterology . 1981;81:247–256
  235. Moreaux J , Bougaran J . Early gastric cancer (A 25-year surgical experience) . Ann Surg . 1993;217:347–355
  236. Lawrence M , Shiu MH . Early gastric cancer (Twenty-eight-year experience) . Ann Surg . 1991;213:327–334
  237. Okuda H , Suzuki S , Suzuki H , Kurokawa K , Kitamura Y , Mitsunaga A , et al.   Diagnosis and prognosis of early gastric cancer: the experience in Japan . Trop Gastroenterol . 1988;9:7–13
  238. Gebhardt C , Husemann B , Hermanek P , Gentsch HH . Clinical aspects and therapy of early gastric cancer . World J Surg . 1981;5:721–724
  239. Sano T , Katai H , Sasako M , Maruyama K . The management of early gastric cancer . Surg Oncol . 2000;9:17–22
  240. Kuwayama H , Eastwood GL , Kohashi E , Honda T . Endoscopic local injection of early gastric carcinoma with 5-fluorouracil . Dig Dis Sci . 1984;29:498–501
  241. Sakita T , Koyama S , Ishii M , Togo J , Miyamoto J , Nakahara A , et al.   Early cancer of the stomach treated successfully with an endoscopic neodymium-YAG laser: report of a case . Am J Gastroenterol . 1981;76:441–445
  242. Kitagawa Y , Fujii H , Mukai M , Kubota T , Otani Y , Kitajima M . Radio-guided sentinel node detection for gastric cancer . Br J Surg . 2002;89:604–608
  243. Seto Y , Yamaguchi H , Shimoyama S , Shimizu N , Aoki F , Kaminishi M . Results of local resection with regional lymphadenectomy for early gastric cancer . Am J Surg . 2001;182:498–501
  244. Kitano S , Shiraishi N . Minimally invasive surgery for gastric tumors . Surg Clin North Am . 2005;85:151–164 xi
  245. Huscher CG , Mingoli A , Sgarzini G , Sansonetti A , Di Paola M , Recher A , et al.   Laparoscopic versus open subtotal gastrectomy for distal gastric cancer: five-year results of a randomized prospective trial . Ann Surg . 2005;241:232–237
  246. ReMine WH . Palliative operations for incurable gastric cancer . World J Surg . 1979;3:721–729
  247. Miner TJ , Jaques DP , Karpeh MS , Brennan MF . Defining palliative surgery in patients receiving noncurative resections for gastric cancer . J Am Coll Surg . 2004;198:1013–1021
  248. Haugstvedt T , Viste A , Eide GE , Soreide O . The survival benefit of resection in patients with advanced stomach cancer: the Norwegian multicenter experience (Norwegian Stomach Cancer Trial) . World J Surg . 1989;13:617–621
  249. Monson JR , Donohue JH , McIlrath DC , Farnell MB , Ilstrup DM . Total gastrectomy for advanced cancer (A worthwhile palliative procedure) . Cancer . 1991;68:1863–1868
  250. Boddie AW , McMurtrey MJ , Giacco GG , McBride CM . Palliative total gastrectomy and esophagogastrectomy (A reevaluation) . Cancer . 1983;51:1195–1200
  251. Bozzetti F , Bonfanti G , Audisio RA , Doci R , Dossena G , Gennari L , et al.   Prognosis of patients after palliative surgical procedures for carcinoma of the stomach . Surg Gynecol Obstet . 1987;164:151–154
  252. Cosentini EP , Sautner T , Gnant M , Winkelbauer F , Teleky B , Jakesz R . Outcomes of surgical, percutaneous endoscopic, and percutaneous radiologic gastrostomies . Arch Surg . 1998;133:1076–1083
  253. Dormann AJ . Endoscopic palliation and nutritional support in advanced gastric cancer . Dig Dis . 2004;22:351–359
  254. Sarela AI , Miner TJ , Karpeh MS , Coit DG , Jaques DP , Brennan MF . Clinical outcomes with laparoscopic stage M1, unresected gastric adenocarcinoma . Ann Surg . 2006;243:189–195
  255. Macdonald JS , Schein PS , Woolley PV , Smythe T , Ueno W , Hoth D , et al.   5-Fluorouracil, doxorubicin, and mitomycin (FAM) combination chemotherapy for advanced gastric cancer . Ann Intern Med . 1980;93:533–536
  256. Preusser P , Achterrath W , Wilke H , Lenaz L , Fink U , Heinicke A , et al.   Chemotherapy of gastric cancer . Cancer Treat Rev . 1988;15:257–277
  257. Ogawa M . A recent overview of chemotherapy for advanced stomach cancer in Japan . Antibiot Chemother . 1978;24:149–159
  258. Cocconi G , DeLisi V , Di BB . Randomized comparison of 5-FU alone or combined with mitomycin and cytarabine (MFC) in the treatment of advanced gastric cancer . Cancer Treat Rep . 1982;66:1263–1266
  259. Cullinan SA , Moertel CG , Fleming TR , Rubin JR , Krook JE , Everson LK , et al.   A comparison of three chemotherapeutic regimens in the treatment of advanced pancreatic and gastric carcinoma (Fluorouracil vs fluorouracil and doxorubicin vs fluorouracil, doxorubicin, and mitomycin) . JAMA . 1985;253:2061–2067
  260. Klein HO . Long-term results with FAMTX (5-fluorouracil, adriamycin, methotrexate) in advanced gastric cancer . Anticancer Res . 1989;9:1025–1026
  261. Wils JA , Klein HO , Wagener DJ , Bleiberg H , Reis H , Korsten F , et al.   Sequential high-dose methotrexate and fluorouracil combined with doxorubicin–a step ahead in the treatment of advanced gastric cancer: a trial of the European Organization for Research and Treatment of Cancer Gastrointestinal Tract Cooperative Group . J Clin Oncol . 1991;9:827–831
  262. Kelsen DP , Buckner J , Einzig A , Magill G , Heelan R , Vinciguerra V . Phase II trial of cisplatin and etoposide in adenocarcinomas of the upper gastrointestinal tract . Cancer Treat Rep . 1987;71:329–330
  263. Preusser P , Wilke H , Achterrath W , Fink U , Lenaz L , Heinicke A , et al.   Phase II study with the combination etoposide, doxorubicin, and cisplatin in advanced measurable gastric cancer . J Clin Oncol . 1989;7:1310–1317
  264. Wilke H , Preusser P , Fink U , Achterrath W , Meyer HJ , Stahl M , et al.   New developments in the treatment of gastric carcinoma . Semin Oncol . 1990;17(1 Suppl 2):61–70
  265. Vanhoefer U , Rougier P , Wilke H , Ducreux MP , Lacave AJ , Van CE , et al.   Final results of a randomized phase III trial of sequential high-dose methotrexate, fluorouracil, and doxorubicin versus etoposide, leucovorin, and fluorouracil versus infusional fluorouracil and cisplatin in advanced gastric cancer: A trial of the European Organization for Research and Treatment of Cancer Gastrointestinal Tract Cancer Cooperative Group . J Clin Oncol . 2000;18:2648–2657
  266. Cunningham D , Cahn A , Menzies-Gow N . Cisplatin, epirubicin and 5-fluorouracil (CEF) has significant activity in advance gastric cancer . Proc ASCO . 1990;9:123
  267. Waters JS , Norman A , Cunningham D , Scarffe JH , Webb A , Harper P , et al.   Long-term survival after epirubicin, cisplatin and fluorouracil for gastric cancer: results of a randomized trial . Br J Cancer . 1999;80(1-2):269–272
  268. Moiseyenko VM , Ajani JA , Tjulandin A , Majlis M , Consela C , Boni A . Final results of a randomized controlled phase III trial (TAX 325) comparing docetaxel (T) combined with cisplatin (C) and 5-flurouracil (F) to CF in patients with metastatic gastric adenocarcinoma . Proc ASCO . 2005;43:308
  269. Wagner AD , Grothe W , Behl S , Kleber G , Grothey A , Haerting J , et al.   Chemotherapy for advanced gastric cancer . Cochrane Database Syst Rev . 2005;(2): CD004064
  270. Boku N , Chin K , Hosokawa K , Ohtsu A , Tajiri H , Yoshida S , et al.   Biological markers as a predictor for response and prognosis of unresectable gastric cancer patients treated with 5-fluorouracil and cis-platinum . Clin Cancer Res . 1998;4:1469–1474
  271. The Gastrointestinal Tumor Study Group . The concept of locally advanced gastric cancer (Effect of treatment on outcome) . Cancer . 1990;66:2324–2330
  272. Higgins GA , Amadeo JH , Smith DE , Humphrey EW , Keehn RJ . Efficacy of prolonged intermittent therapy with combined 5-FU and methyl-CCNU following resection for gastric carcinoma (A Veterans Administration Surgical Oncology, Group report) . Cancer . 1983;52:1105–1112
  273. Lise M , Nitti D , Marchet A , Sahmoud T , Buyse M , Duez N , et al.   Final results of a phase III clinical trial of adjuvant chemotherapy with the modified fluorouracil, doxorubicin, and mitomycin regimen in resectable gastric cancer . J Clin Oncol . 1995;13:2757–2763
  274. Macdonald JS , Fleming TR , Peterson RF , Berenberg JL , McClure S , Chapman RA , et al.   Adjuvant chemotherapy with 5-FU, adriamycin, and mitomycin-C (FAM) versus surgery alone for patients with locally advanced gastric adenocarcinoma: A Southwest Oncology Group study . Ann Surg Oncol . 1995;2:488–494
  275. Imanaga H , Nakazato H . Results of surgery for gastric cancer and effect of adjuvant mitomycin C on cancer recurrence . World J Surg . 1977;2:213–221
  276. Nakajima T , Takahashi T , Takagi K , Kuno K , Kajitani T . Comparison of 5-fluorouracil with ftorafur in adjuvant chemotherapies with combined inductive and maintenance therapies for gastric cancer . J Clin Oncol . 1984;2:1366–1371
  277. Hermans J , Bonenkamp JJ , Boon MC , Bunt AM , Ohyama S , Sasako M , et al.   Adjuvant therapy after curative resection for gastric cancer: meta-analysis of randomized trials . J Clin Oncol . 1993;11:1441–1447
  278. Earle CC , Maroun JA . Adjuvant chemotherapy after curative resection for gastric cancer in non-Asian patients: revisiting a meta-analysis of randomised trials . Eur J Cancer . 1999;35:1059–1064
  279. Moertel CG , Childs DS , O’Fallon JR , Holbrook MA , Schutt AJ , Reitemeier RJ . Combined 5-fluorouracil and radiation therapy as a surgical adjuvant for poor prognosis gastric carcinoma . J Clin Oncol . 1984;2:1249–1254
  280. Herskovic A , Martz K , al-Sarraf M , Leichman L , Brindle J , Vaitkevicius V , et al.   Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus . N Engl J Med . 1992;326:1593–1598
  281. Macdonald JS , Smalley SR , Benedetti J , Hundahl SA , Estes NC , Stemmermann GN , et al.   Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction . N Engl J Med . 2001;345:725–730
  282. Allum N , Cunningham D , Weeden S  UK NCRI Upper GI Clinical Studies Group . Peri-operative chemotherapy in operable gastric and lower esophageal cancer: randomised controlled trial (the Magic Trial) . Proc ASCO . 2005;22:249

PII: S0011-3840(06)00063-3

doi: 10.1067/j.cpsurg.2006.06.003

Current Problems in Surgery
Volume 43, Issue 8 , Pages 566-670 , August 2006

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